Luxury Homes for Sale in the 80221 Zip Code
View all luxury homes and real estate for sale now in the 80221 zip code. These luxury 80221 home listings are updated daily with data from our local Multiple Listing Service (MLS). Information here includes photos, property descriptions, pricing information and details about the homes and neighborhoods. You’ll also see maps and nearby properties for sale. Schedule a tour online anytime. To learn more about any 80221 homes for sale, call or text The Principal Team at 720-408-7409 or contact us.
All Luxury 80221 Homes & Real Estate For Sale
Unincorporated Adams County 200
5711 Hooker Street, Denver, CO 80221
3Bedroom(s)
1Bathroom(s)
5Parking(s)
37Picture(s)
600 SquareFeet
sprawling 1.23 acres in a desirable Berkley community, this incredible industrial property along the scenic banks of Clear Creek in Adams County is one you’ll need to see to believe! Registered as I-2, this rare find includes a recently renovated 3-bedroom, 1-bath home, a well-sized workshop, and generous grounds bursting with potential.
$1,500,000
SUB: PETE ROMERO LOT:1
3595 W 67th Avenue, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
8Parking(s)
34Picture(s)
3,040 SquareFeet
Welcome this beautiful and unique single-family ranch home situated on a corner lot with captivating mountain and lake views and NO HOA’s.
$949,900
Berkeley
4966 Knox Court, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
3Parking(s)
50Picture(s)
3,240 SquareFeet
Modern Luxury Meets Investment Potential – Turnkey Retreat Across from Regis University! Incredible opportunity to own a one of a kind modern 5BR/4BA home in Denver, previously a top-rated Airbnb! This property is offered fully furnished with a full-price offer, including all furniture, linens, kitchenware, and high-end appliances, making it ideal as a turnkey luxury Airbnb or a move-in ready ne
$1,591,000
Clear Creek Gardens
3165 W 63rd Avenue, Denver, CO 80221
6Bedroom(s)
4Bathroom(s)
3Parking(s)
31Picture(s)
3,460 SquareFeet
2-story home built in 2024 * 6 bedrooms, 4 bath & 3 insulated car garage * 9 to 10 foot ceilings throughout entire home * Separate entrance to Basement, so it could be rented out between $1500 and $2,000 per month * Low Taxes & No HOA * MAIN FLOOR: living room with fireplace, next to the family room with floor-to-ceiling windows & 20-foot-high vaulted ceilings, next to formal dining space & kitche
$1,015,000
UNINCORPORATED ADAMS COUNTY
1195 W 70th Avenue, Denver, CO 80221
5Bedroom(s)
4Bathroom(s)
3Parking(s)
40Picture(s)
3,596 SquareFeet
This is the one you’ve been waiting for! A rare opportunity in unincorporated Adams County — this spacious 5-bedroom, 4-bath home sits on a large A1-zoned lot with endless potential and possibilities.**
Home office or business with yard storage for equipment?**
Room to add a pool, pickleball court, or tennis court?**
The options are nearly unlimited.
$1,299,950
Midtown at Clear Creek
6760 Mariposa Court, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
39Picture(s)
3,072 SquareFeet
Welcome to this beautifully maintained 4-bedroom, 4-bathroom single-family home in the heart of Midtown! Thoughtfully designed for both comfort and functionality, this spacious residence offers flexible living across three levels with a whole-house humidifier for those dry Colorado days.
$800,000
Clear Creek Gardens
3165 W 63rd Avenue, Denver, CO 80221
6Bedroom(s)
4Bathroom(s)
3Parking(s)
31Picture(s)
3,460 SquareFeet
2-story home built in 2024 * 6 bedrooms, 4 bath & 3 insulated car garage * 9 to 10 foot ceilings throughout entire home * Separate entrance to Basement, so it could be rented out between $1500 and $2,000 per month * Low taxes & No HOA fee * MAIN FLOOR: living room with fireplace, next to the family room with floor-to-ceiling windows & 20-foot-high vaulted ceilings, next to formal dining space & ki
$1,015,000
North Lowell Heights
3440 W 66th Avenue, Denver, CO 80221
3Bedroom(s)
2Bathroom(s)
12Parking(s)
7Picture(s)
1,620 SquareFeet
Excellent opportunity for a 1 acre lot! Nice property for a creative buyer who can transform it into a dream house! R-2 zoning allows for a duplex to be built. Easy access to highways and bus stops, close to shopping area. Lots of space for all your trucks and toys.
$1,000,000