Luxury Homes for Sale in the 80221 Zip Code
View all luxury homes and real estate for sale now in the 80221 zip code. These luxury 80221 home listings are updated daily with data from our local Multiple Listing Service (MLS). Information here includes photos, property descriptions, pricing information and details about the homes and neighborhoods. You’ll also see maps and nearby properties for sale. Schedule a tour online anytime. To learn more about any 80221 homes for sale, call or text The Principal Team at 720-408-7409 or contact us.
All Luxury 80221 Homes & Real Estate For Sale
Berkeley Gardens
5383 Meade Street, Denver, CO 80221
5Bedroom(s)
4Bathroom(s)
2Parking(s)
32Picture(s)
2,786 SquareFeet
Experience the perfect fusion of 1940s charm and 2025 modern construction standards in this brand-new, versatile home located within Denver city limits. Boasting 5 spacious bedrooms and 3.5 beautifully appointed bathrooms, this home is ideal for multi-generational living or anyone seeking ample space with timeless character.
$959,900
Berkeley Gardens
5326 Lowell Boulevard, Denver, CO 80221
4Bedroom(s)
3Bathroom(s)
1Parking(s)
27Picture(s)
1,782 SquareFeet
Welcome to one of the best opportunities in the prestigious Regis neighborhood.
Here you can enjoy a timeless 3/2 residence as well as a new 1 car garage with a 1/1 apartment above (currently rented for $1700/mo).
$895,000
Midtown at Clear Creek
6752 Mariposa, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
39Picture(s)
3,514 SquareFeet
Rare one-of-a-kind home backing to open space, with views of Downtown & open space. Completely remodeled & move-in ready. Open floor plan, light & bright with an abundance of natural light that floods the entire home all day through the homes large windows in every room. Up/Down high end window blinds & custom treatments througout.
$1,010,000
Berkeley
4942 Grove Street, Denver, CO 80221
5Bedroom(s)
4Bathroom(s)
2Parking(s)
43Picture(s)
2,569 SquareFeet
Prime House Hack Opportunity in Denver’s Sought-After Berkeley Neighborhood. 1 block North of highway I-70, providing convenience to anywhere in Colorado.
Welcome to a stunning and versatile home in one of Denver’s most desirable areas. This spacious property is the ultimate house hack, offering both comfortable living and income-generating potential.
$1,250,000
Midtown at Clear Creek
1730 W 67th Avenue, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
48Picture(s)
3,114 SquareFeet
Welcome to 1730 W 67th Ave — a stylish and spacious 4 bedroom, 3.5 bathroom home nestled in the heart of the vibrant Midtown community.
$815,000
Midtown
1813 W 67th Avenue, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
41Picture(s)
2,744 SquareFeet
What’s better than a gorgeous, high-end 4-bedroom home in Denver’s Midtown neighborhood? Not much—except scoring one on a rare, spacious corner lot just one block from the community’s popular park, splash pad, coffee shop, and brewery! This home’s prime location offers easy access to downtown in just 10 minutes, along with proximity to the Clear Creek path, major commuting routes, and th
$820,000
Clear Creek Gardens Sub
3165 W 63rd Avenue, Denver, CO 80221
6Bedroom(s)
4Bathroom(s)
3Parking(s)
31Picture(s)
3,460 SquareFeet
2-story home built in 2024 * 6 bedrooms, 4 bath & 3 insulated car garage * 9 to 10 foot ceilings throughout entire home * Separate entrance to Basement, so it could be rented out between $1500 and $2,000 per month * Low taxes & No HOA fees * MAIN FLOOR: living room with fireplace, next to the family room with floor-to-ceiling windows & 20-foot-highvaulted ceilings, next to formal dining space & ki
$1,049,500
Clear Creek Gardens
3165 W 63rd Avenue, Denver, CO 80221
6Bedroom(s)
4Bathroom(s)
3Parking(s)
31Picture(s)
3,460 SquareFeet
2-story home built in 2024 * 6 bedrooms, 4 bath & 3 insulated car garage * 9 to 10 foot ceilings throughout entire home * Separate entrance to Basement, so it could be rented out between $1500 and $2,000 per month * Low taxes & No HOA fee * MAIN FLOOR: living room with fireplace, next to the family room with floor-to-ceiling windows & 20-foot-high vaulted ceilings, next to formal dining space & ki
$1,049,500
Midtown at Clear Creek
6619 Mariposa Court, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
50Picture(s)
3,082 SquareFeet
Welcome to Your Dream Home in Midtown at Clear Creek! This exceptional residence, crafted by the renowned David Weekley Homes, seamlessly combines modern elegance with comfortable living. Situated on one of the largest lots in Midtown, this home offers an expansive backyard that’s perfect for both relaxation and entertainment.
$835,000
Midtown
6877 Bryant Court, Denver, CO 80221
3Bedroom(s)
4Bathroom(s)
2Parking(s)
21Picture(s)
2,298 SquareFeet
Last Chance to Move In This Year – Brand-New 3-Story End-Unit Townhome with Rooftop Deck by Brookfield Residential in Midtown
**Contact Sales to Learn More About the $40,000 Finance Credit! **
Don’t miss your final opportunity to move into Midtown in 2025—this stunning end-unit Horizon Townhome by Brookfield Residential is move-in ready this summer, and one of the last available homes that
$805,096
Midtown
6880 Bryant Way, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
15Picture(s)
2,632 SquareFeet
FINAL OPPORTUNITY – Only 9 Townhomes Remaining!
Brand-New Horizon END-UNIT Townhome by Brookfield Residential at Midtown – Move-in Summer 2025!
Don’t miss your chance to own one of the last remaining Horizon townhomes in Midtown! This stunning end-unit three-story home offers 4 bedrooms, 4 bathrooms, plus a small office—perfect for remote work, hosting guests, or simply relaxing in com
$845,682
Midtown at Clear Creek
6715 Raritan Drive, Denver, CO 80221
6Bedroom(s)
6Bathroom(s)
3Parking(s)
50Picture(s)
3,406 SquareFeet
Luxury 6-Bedroom Home with High-End Upgrades, Smart Features & Outdoor Space!
Welcome to this stunning 6-bedroom, 6-bathroom home, designed for ultimate comfort, convenience, and style. This thoughtfully updated residence features two master suites, each with a walk-in closet and private bath, making it ideal for multi-generational living or for hosting guests in style.
$920,000