Metro Denver Luxury Homes For Sale

Property Description

Rare and storied mixed-use opportunity situated on a highly visible 6,270-square-foot corner lot in the heart of Five Points. The property features a historic five-bedroom residence and a separate office building, totaling approximately 6,565 square feet of improvements on a single parcel. Ideally positioned just steps from Benedict Fountain Park, the RTD 27th & Welton Light Rail Station, neighborhood coffee shops and restaurants, and only minutes from Downtown Denver and Uptown, the property offers an exceptional blend of urban convenience, historic character, and neighborhood connectivity. The property includes an approximately 2,565-square-foot historic residence with five bedrooms and two bathrooms, currently operating as a successful Airbnb and providing immediate income or the opportunity for owner occupancy. Tucked behind the residence is a rare, private rear
patio, offering an inviting outdoor retreat ideal for entertaining, relaxing, or complementing a live/work lifestyle—an uncommon amenity for a property so close to downtown. Complementing the residence is a separate office duplex totaling approximately 4,000 square feet, comprised of two approximately 2,000-square-foot office suites, one of which is currently leased on a month-to-month basis, providing immediate cash flow while preserving flexibility for future occupancy, repositioning, or redevelopment.
Located within the Clements Historic District, this unique property offers exceptional visibility, walkability, and access to some of Denver’s most desirable dining, entertainment, cultural, and transit amenities. Whether envisioned as an investment, corporate headquarters with supplemental income, creative office campus, live/work environment, boutique hospitality concept, or long-term repositioning opportunity, this one-of-a-kind asset presents remarkable versatility in one of Denver’s most vibrant and historically significant neighborhoods.

Features
: Hot Water
: None
: Composition
: Public Sewer
Address Map
CO
Denver
Denver
80205
21st
422
Street
W105° 0' 56.4''
N39° 44' 53.7''
Additional Information
: Brick
2
Whittier E-8
East
Yes
Yes
Cash, Conventional
: Level
Cole Arts And Science Academy
Kentwood Commercial, Llc
2341-27-015
: None
: House
Five Points
$15,636
2024
C-MX-5
02/10/2026
2565
Active
Denver 1
Denver 1
Denver 1
07/24/2026
06/24/2026
: Two

Five Points

422 21st Street, Denver, CO 80205

4 Bedrooms
2 Total Baths
2,565 Square Feet
$1,100,000
Listing ID #6487194
Basic Details
Property Type : Residential
Listing Type : For Sale
Listing ID : 6487194
Price : $1,100,000
Bedrooms : 4
Rooms : 8
Total Baths : 2
Full Bathrooms : 1
3/4 Bathrooms : 1
Square Footage : 2,565 Square Feet
Year Built : 1886
Lot Area : 6,270 Acres
Lot Acres : 0.14
Property Sub Type : Single Family Residence
Status : Active
Originating System Name : REcolorado
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