Luxury Homes for Sale in the 80221 Zip Code
View all luxury homes and real estate for sale now in the 80221 zip code. These luxury 80221 home listings are updated daily with data from our local Multiple Listing Service (MLS). Information here includes photos, property descriptions, pricing information and details about the homes and neighborhoods. You’ll also see maps and nearby properties for sale. Schedule a tour online anytime. To learn more about any 80221 homes for sale, call or text The Principal Team at 720-408-7409 or contact us.
All Luxury 80221 Homes & Real Estate For Sale
Midtown
6864 Bryant Court, Denver, CO 80221
3Bedroom(s)
4Bathroom(s)
2Parking(s)
25Picture(s)
2,298 SquareFeet
Live above it all in this stunning, brand-new Horizon Townhome by Brookfield Residential—complete with a private rooftop deck, designer finishes, and a $40,000 seller concession to help lower your monthly payments! Move-in ready this July.
$827,815
SUB: PETE ROMERO LOT:1
3595 W S 67th Avenue, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
8Parking(s)
42Picture(s)
3,040 SquareFeet
Welcome this beautiful and unique single-family ranch home situated on a corner lot with captivating mountain and lake views and NO HOA’s.
$1,150,000
Midtown at Clear Creek
1345 W 67th Place, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
31Picture(s)
3,507 SquareFeet
Come on in and see this gorgeous, rare home with the biggest floor plan of the David Weekly Homes in the fun Midtown Neighborhood. It has a lovely open feel when you first walk through the doors with the kitchen, dining room, and living room on the main floor seamlessly flowing together with tons of natural light.
$885,000
Midtown at Clear Creek
1882 W 67th Avenue, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
3Parking(s)
50Picture(s)
3,188 SquareFeet
A rare offering, this coveted Brookfield Signature 5 model commands attention on a professionally landscaped corner lot. Framed by mature ornamental peach trees, the private yard offers an intimate retreat with an extended patio and hot tub, and a concrete hot tub pad—ideal for golden-hour gatherings and alfresco summer evenings beneath the Southwestern sun.
$862,000
Berkeley Gardens
5383 Meade Street, Denver, CO 80221
5Bedroom(s)
4Bathroom(s)
2Parking(s)
34Picture(s)
2,786 SquareFeet
Experience the perfect fusion of 1940s charm and 2025 modern construction standards in this brand-new, versatile home located within Denver city limits. Boasting 5 spacious bedrooms and 3.5 beautifully appointed bathrooms, this home is ideal for multi-generational living or anyone seeking ample space with timeless character.
$920,000
Berkeley Gardens
5326 Lowell Boulevard, Denver, CO 80221
4Bedroom(s)
3Bathroom(s)
1Parking(s)
27Picture(s)
1,782 SquareFeet
INCOME PRODUCING PROPERTY!! MULTIPLE FAMILY HOME!! SAVE $1,700 ON YOUR MORTGAGE!! Welcome to one of the best opportunities in the prestigious Regis neighborhood.
Here you can enjoy a timeless 3/2 residence as well as a new 1 car garage with an ADDITIONAL 600 SQ FT apartment above, that includes 1 bedroom, 1 bathroom, full kitchen and living room.(currently rented for $1700/mo).
$875,000
Midtown at Clear Creek
6752 Mariposa, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
39Picture(s)
3,514 SquareFeet
Rare one-of-a-kind home backing to open space, with views of Downtown & open space. Completely remodeled & move-in ready. Open floor plan, light & bright with an abundance of natural light that floods the entire home all day through the homes large windows in every room. Up/Down high end window blinds & custom treatments througout.
$1,010,000
Berkeley
4942 Grove Street, Denver, CO 80221
5Bedroom(s)
4Bathroom(s)
2Parking(s)
43Picture(s)
2,569 SquareFeet
MOTIVATED SELLER!!!!! PASSIVE INCOME TO EFFORTLESSLY OFFSET YOUR MORTGAGE. Prime House Hack Opportunity in Denver’s Sought-After Berkeley Neighborhood. 1 block North of highway I-70, providing convenience to anywhere in Colorado.
Welcome to a stunning and versatile home in one of Denver’s most desirable areas.
$1,199,500
Clear Creek Gardens Sub
3165 W 63rd Avenue, Denver, CO 80221
6Bedroom(s)
4Bathroom(s)
3Parking(s)
31Picture(s)
3,460 SquareFeet
2-story home built in 2024 * 6 bedrooms, 4 bath & 3 insulated car garage * 9 to 10 foot ceilings throughout entire home * Separate entrance to Basement, so it could be rented out between $1500 and $2,000 per month * Low taxes & No HOA fees * MAIN FLOOR: living room with fireplace, next to the family room with floor-to-ceiling windows & 20-foot-highvaulted ceilings, next to formal dining space & ki
$1,049,500
Clear Creek Gardens
3165 W 63rd Avenue, Denver, CO 80221
6Bedroom(s)
4Bathroom(s)
3Parking(s)
31Picture(s)
3,460 SquareFeet
2-story home built in 2024 * 6 bedrooms, 4 bath & 3 insulated car garage * 9 to 10 foot ceilings throughout entire home * Separate entrance to Basement, so it could be rented out between $1500 and $2,000 per month * Low taxes & No HOA fee * MAIN FLOOR: living room with fireplace, next to the family room with floor-to-ceiling windows & 20-foot-high vaulted ceilings, next to formal dining space & ki
$1,049,500
Midtown at Clear Creek
6619 Mariposa Court, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
50Picture(s)
3,082 SquareFeet
Welcome to Your Dream Home in Midtown at Clear Creek! This exceptional residence, crafted by the renowned David Weekley Homes, seamlessly combines modern elegance with comfortable living. Situated on one of the largest lots in Midtown, this home offers an expansive backyard that’s perfect for both relaxation and entertainment.
$830,000
Midtown
6880 Bryant Way, Denver, CO 80221
4Bedroom(s)
4Bathroom(s)
2Parking(s)
15Picture(s)
2,632 SquareFeet
FINAL OPPORTUNITY – Only 9 Townhomes Remaining!
Brand-New Horizon END-UNIT Townhome by Brookfield Residential at Midtown – Move-in Summer 2025!
Don’t miss your chance to own one of the last remaining Horizon townhomes in Midtown! This stunning end-unit three-story home offers 4 bedrooms, 4 bathrooms, plus a small office—perfect for remote work, hosting guests, or simply relaxing in com
$845,682